Eric Dane Dead at 53: Grey's Anatomy and Euphoria Star Passes Away After ALS Battle

February 20, 2026 – Hollywood is mourning the loss of one of its most charismatic stars. Eric Dane, best known for his unforgettable roles as Dr. Mark Sloan ("McSteamy") on Grey's Anatomy and Cal Jacobs on Euphoria, has passed away at the age of 53.

According to a statement shared with People magazine, Dane died on February 19, 2026, nearly one year after revealing his diagnosis with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

Eric Dane as Dr. Mark Sloan (McSteamy) on Grey's Anatomy smiling in scrubs — Eric Dane captured hearts as the charming Dr. Mark Sloan on Grey's Anatomy. (Credit: ABC)

A Career That Defined an Era

Eric Dane rose to fame in the mid-2000s when he joined the cast of Grey's Anatomy in season 2. His portrayal of the confident plastic surgeon Mark Sloan earned him the nickname "McSteamy" and made him a fan favorite for years. After leaving the show, Dane continued to deliver powerful performances, most notably as the complex Cal Jacobs in HBO's hit series Euphoria.

Throughout his career, Dane showed remarkable range, balancing charm, intensity, and vulnerability in ways that resonated with millions of viewers.

Eric Dane with his daughters Billie and Georgia at a movie premiere — Eric Dane with his daughters Billie (left) and Georgia (right) – family was always his greatest priority. (Credit: Getty Images)

A Courageous Battle with ALS

In April 2025, Dane courageously shared his ALS diagnosis with the world. Over the following months, he became an advocate for awareness and research, even as the disease progressed. He spoke openly about the challenges while maintaining his characteristic grace and determination.

Blue ALS awareness ribbon with floral design symbolizing hope and support — The blue ribbon represents solidarity with those fighting ALS. Dane's advocacy helped shine a light on this devastating disease.

"With heavy hearts, we share that Eric Dane has passed away. He fought bravely and inspired so many along the way."

– Family statement shared exclusively with People

Dane is survived by his two daughters, Billie and Georgia, whom he shared with ex-wife Rebecca Gayheart. The family has requested privacy during this difficult time.

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